What Happens to the Body When It Is Testosterone Deficient?

Testosterone is often thought of as the “male hormone,” but the truth is that both men and women depend on it for health and vitality. Testosterone influences far more than muscle mass or sex drive—it plays a critical role in mood, metabolism, bone strength, and even brain function.

When the body becomes testosterone deficient, the changes can be profound. At Sheen Vein (Aesthetics and Functional Medicine) in St. Louis, we often see patients struggling with fatigue, weight gain, mood changes, or low libido—symptoms that turn out to be rooted in low testosterone.

Let’s take a closer look at what happens inside the body when testosterone levels drop and why addressing this imbalance can restore health and quality of life.

The Role of Testosterone in the Body

Testosterone is produced mainly in the testes in men and in smaller amounts by the ovaries and adrenal glands in women. Its functions extend well beyond reproduction:

  • Supports muscle growth and strength
  • Maintains bone density
  • Regulates fat metabolism
  • Enhances mood and motivation
  • Influences libido and sexual health
  • Affects cognitive function and memory

When levels fall below optimal, these systems begin to show signs of strain.

Physical Effects of Testosterone Deficiency

1. Muscle Loss and Weakness

Testosterone is anabolic—it helps build and maintain muscle. Low levels lead to decreased muscle mass, less strength, and slower recovery after exercise or injury. Many patients notice that workouts don’t produce results the way they used to.

2. Increased Body Fat

Without enough testosterone, metabolism slows and fat storage increases, particularly in the abdominal area. This central or “visceral” fat is linked with higher risk for diabetes and cardiovascular disease.

3. Reduced Bone Density

Testosterone stimulates bone growth. Deficiency can accelerate bone loss, raising the risk of osteoporosis and fractures, especially in aging men.

4. Low Energy and Fatigue

Testosterone plays a key role in mitochondrial function—the energy-producing engines inside cells. Deficiency often leads to chronic fatigue, lower stamina, and less motivation.

Cognitive and Emotional Changes

1. Brain Fog and Poor Concentration

Low testosterone is linked to reduced cognitive function, including memory lapses, slower thinking, and difficulty focusing.

2. Mood Changes

Deficiency often contributes to irritability, anxiety, and even depression. Because testosterone influences brain chemistry, patients frequently describe feeling “flat” or emotionally unstable.

3. Loss of Motivation

Many men and women with low testosterone report a lack of drive, ambition, or enjoyment in daily activities.

Sexual Health Effects

Testosterone deficiency has perhaps the most recognized impact on sexual function:

  • Men – Low libido, erectile dysfunction, or reduced morning erections.
  • Women – Decreased sexual desire, vaginal dryness, and less satisfaction during intimacy.

These changes can affect confidence, relationships, and overall quality of life.

Other Signs of Testosterone Deficiency

  • Sleep disturbances – Poor sleep quality or insomnia
  • Hair thinning – Especially on the scalp or body
  • Slower healing – Cuts, injuries, and even workouts take longer to recover from
  • Hot flashes or night sweats – More common in women, but can affect men as well

Long-Term Risks of Untreated Low Testosterone

Beyond day-to-day symptoms, prolonged testosterone deficiency can increase long-term health risks, including:

  • Osteoporosis – Fragile bones and higher fracture risk
  • Metabolic Syndrome – Increased abdominal fat, high blood pressure, and insulin resistance
  • Cardiovascular Disease – Studies suggest low testosterone is associated with higher rates of heart disease
  • Cognitive Decline – Low levels may contribute to memory loss or dementia risk

This is why testosterone deficiency is more than just an inconvenience—it’s a medical issue that deserves evaluation and treatment.

How We Address Testosterone Deficiency

At Sheen Vein (Aesthetics and Functional Medicine), we use a functional medicine approach to uncover the root causes of low testosterone and restore balance safely. Our process includes:

  1. Comprehensive Testing – Measuring total testosterone, free testosterone, SHBG, estradiol, thyroid, and adrenal hormones.
  2. Lifestyle and Nutritional Support – Sleep optimization, strength training, stress management, and key nutrients like zinc and vitamin D.
  3. Hormone Replacement Therapy (HRT) – When needed, we prescribe carefully monitored bioidentical testosterone therapy, customized in dose and delivery method (injections, creams, or pellets).
  4. Ongoing Monitoring – Regular follow-ups to ensure safe and effective optimization.

By restoring testosterone levels, patients often regain energy, focus, sexual health, and resilience.

Final Thoughts

Testosterone deficiency affects the whole body—from muscles and bones to mood and memory. Left unaddressed, it not only lowers quality of life but also increases long-term health risks.

At Sheen Vein (Aesthetics and Functional Medicine) in St. Louis, we specialize in identifying hormone imbalances and creating personalized plans to restore balance. If you’ve been feeling unlike yourself, don’t ignore the possibility of testosterone deficiency. With the right evaluation and treatment, you can reclaim your strength, vitality, and confidence.