What Causes Prediabetes? Understanding the Early Warning Signs and Root Causes

Introduction

Prediabetes is your body’s warning light. It means your blood sugar is no longer in the healthy range—but it hasn’t crossed into type 2 diabetes just yet. While it may sound harmless, prediabetes is a critical red flag that should never be ignored.

According to the CDC, more than 96 million U.S. adults—about 1 in 3—have prediabetes, and over 80% don’t even know they have it. Left unchecked, prediabetes can silently damage your heart, blood vessels, nerves, and metabolism for years before full-blown diabetes develops.

In this blog, we’ll explore:

  • What prediabetes is (and how it's diagnosed)
  • The key causes and risk factors
  • Functional medicine's root-cause approach
  • How to reverse prediabetes naturally before it becomes diabetes

What Is Prediabetes?

Prediabetes occurs when your blood glucose levels are elevated, but not high enough for a diagnosis of type 2 diabetes.

Diagnostic criteria:

  • Fasting glucose: 100–125 mg/dL
  • Hemoglobin A1c: 5.7–6.4%
  • 2-hour glucose tolerance test: 140–199 mg/dL

These numbers show that your body is having trouble keeping blood sugar in check—often due to insulin resistance, where cells no longer respond efficiently to insulin's signal to absorb glucose.

Why Prediabetes Matters

Prediabetes isn’t just a stepping stone to diabetes—it comes with its own serious risks, including:

  • Increased risk of heart disease and stroke
  • Nerve damage and early neuropathy
  • Fatigue, brain fog, and mood issues
  • Difficulty losing weight or building muscle
  • Higher risk of non-alcoholic fatty liver disease (NAFLD)

The good news? Prediabetes is reversible, especially when addressed early through nutrition, lifestyle, and functional interventions.

What Causes Prediabetes?

Prediabetes is rarely caused by a single issue—it’s usually the result of multiple metabolic stressors over time. Here are the most common root causes:

1. Insulin Resistance

At the core of prediabetes is insulin resistance. This occurs when your body’s cells stop responding properly to insulin, the hormone that moves sugar out of your blood and into your cells for energy.

As resistance builds, your pancreas compensates by pumping out more insulin. Eventually, this system becomes overwhelmed, and blood sugar starts to rise.

What causes insulin resistance?

  • High sugar and refined carb intake
  • Sedentary lifestyle
  • Chronic inflammation
  • Visceral belly fat
  • Poor sleep and chronic stress

2. Poor Diet and Blood Sugar Spikes

Eating a diet high in:

  • Refined carbohydrates (white bread, pasta, pastries)
  • Sugar-sweetened beverages
  • Ultra-processed foods
    causes repeated blood sugar spikes, which overwork your insulin system.

Frequent spikes followed by crashes create a cycle of fatigue, cravings, and eventual metabolic burnout.

3. Lack of Physical Activity

Muscle tissue is one of the most insulin-sensitive parts of your body. When you move your body, you help your muscles absorb glucose—even without insulin.

A sedentary lifestyle reduces this natural insulin sensitivity, allowing blood sugar and insulin levels to climb unchecked.

4. Chronic Stress and High Cortisol

When you're under chronic stress, your adrenal glands produce more cortisol, a hormone that tells your body to raise blood sugar in case of emergency. Over time, this can lead to:

  • Higher fasting glucose
  • Fat storage around the midsection
  • Increased insulin resistance

5. Sleep Deprivation

Poor sleep quality—even for just a few nights—can significantly worsen insulin sensitivity.

Sleep apnea, which is common in people with excess weight or inflammation, further worsens prediabetes by depriving the body of oxygen and disrupting blood sugar regulation overnight.

6. Hormonal Imbalances

Imbalances in estrogen, progesterone, thyroid hormones, or testosterone can influence insulin function.

For example:

  • Women with PCOS often struggle with insulin resistance
  • Low testosterone in men is associated with metabolic syndrome
  • Hypothyroidism slows metabolism and worsens weight gain and insulin sensitivity

7. Visceral Fat and Inflammation

Fat around your midsection (visceral fat) isn’t just extra weight—it’s metabolically active and produces inflammatory chemicals called cytokines.

This chronic low-grade inflammation interferes with insulin signaling and increases your risk of prediabetes and diabetes—even if your BMI is technically “normal.”

8. Genetics and Family History

While lifestyle plays a major role, some people are genetically more prone to insulin resistance.

If you have a family history of:

  • Type 2 diabetes
  • Gestational diabetes
  • High blood pressure or heart disease

…you may have a lower threshold for developing prediabetes and should be extra proactive with prevention.

9. Environmental Toxins

Endocrine-disrupting chemicals found in plastics (BPA), pesticides, and personal care products can interfere with insulin signaling.

These toxins can also contribute to fatty liver, mitochondrial dysfunction, and metabolic slowdown—all of which are linked to blood sugar issues.

Signs and Symptoms of Prediabetes

Prediabetes often develops silently—but there are early warning signs to look for:

  • Fatigue after meals
  • Frequent sugar cravings
  • Brain fog or poor concentration
  • Belly fat that’s hard to lose
  • Skin tags or dark patches (acanthosis nigricans)
  • Increased thirst or urination
  • Mood swings or anxiety
  • Difficulty sleeping

If you have any of these, it’s worth checking your fasting glucose, insulin, and A1c levels—even if you're young or thin.

The Functional Medicine Approach to Reversing Prediabetes

Rather than waiting for a diabetes diagnosis, functional medicine focuses on early detection, root-cause evaluation, and long-term reversal. Here’s how:

1. Personalized Testing

Go beyond A1c with:

  • Fasting insulin and HOMA-IR to measure insulin resistance
  • C-peptide to evaluate pancreatic function
  • CRP and homocysteine to assess inflammation
  • Adiponectin, leptin, cortisol, thyroid, and nutrient panels for full metabolic insight

2. Nutrition to Stabilize Blood Sugar

A blood-sugar-friendly diet includes:

  • Low-glycemic vegetables and whole foods
  • Healthy fats (avocado, olive oil, nuts, seeds)
  • Clean proteins (pasture-raised meats, wild-caught fish)
  • Fiber-rich foods (chia seeds, legumes, leafy greens)

Avoid:

  • Refined carbs and sugar
  • Sweetened beverages
  • Ultra-processed snacks
  • Inflammatory oils (canola, soybean)

3. Exercise for Insulin Sensitivity

  • Strength training 2–4x/week builds muscle and improves glucose uptake
  • Walking after meals helps blunt blood sugar spikes
  • Interval training may boost metabolic flexibility

4. Targeted Supplements

  • Berberine: Works like metformin to lower blood sugar
  • Inositol (especially myo-inositol): Supports insulin signaling
  • Magnesium: Crucial for glucose metabolism
  • Alpha-lipoic acid (ALA): Antioxidant that enhances insulin sensitivity
  • Vitamin D: Low levels are linked to insulin resistance

Always test before supplementing to target what your body actually needs.

5. Address Sleep and Stress

  • Prioritize 7–9 hours of quality sleep per night
  • Address sleep apnea if you snore or wake frequently
  • Practice stress-reducing habits: deep breathing, meditation, yoga, grounding

Conclusion: Prediabetes Is a Wake-Up Call—Not a Life Sentence

Prediabetes is reversible—but only if you act early. By identifying the root causes like insulin resistance, inflammation, poor diet, or stress, you can take meaningful steps to restore your metabolic health and prevent type 2 diabetes altogether.

At Sheen Vein & Cosmetics, we offer a comprehensive, functional approach to blood sugar balance—combining advanced lab testing with personalized nutrition, lifestyle coaching, and targeted natural therapies.

Ready to Take Control of Your Blood Sugar?

Book your functional metabolic consultation today and discover a customized plan to reverse prediabetes and reclaim your health—naturally.

📞 Call now or schedule online to get started.