If you’ve ever felt like you’re doing everything right—eating better, exercising more, cutting calories—but the scale won’t budge, you’re not alone.
Weight loss is about more than just calories in vs. calories out. Many people hit a wall because of hidden imbalances in hormones, metabolism, gut health, or inflammation that block their progress.
In this blog, we’ll explore 10 possible reasons you can’t lose weight, especially from a functional medicine perspective—and what you can do about it.
Insulin is your body’s fat-storage hormone. When your cells become resistant to insulin, your body:
Signs you may be insulin resistant:
✅ Fix it with: Lower-carb, high-fiber meals; intermittent fasting; supplements like berberine or inositol (with medical guidance).
Stress triggers cortisol, which can:
If you're constantly in fight-or-flight mode, your body will prioritize survival over fat loss.
✅ Fix it with: Mindfulness practices, walking, adaptogens (like ashwagandha), better sleep, and blood sugar balance.
Less than 7 hours of sleep per night increases:
Even a few nights of poor sleep can derail your metabolism and increase cravings and fat storage.
✅ Fix it with: Sleep hygiene (dark, cool room), magnesium glycinate, turning off screens an hour before bed, and consistent bedtime routines.
Your thyroid regulates metabolism. If it's underactive (hypothyroidism), you may experience:
Even "normal" TSH levels don’t always mean your thyroid is optimal.
✅ Fix it with: Full thyroid panel (TSH, Free T3, Free T4, reverse T3, antibodies), selenium, zinc, iodine (if appropriate), and targeted thyroid support.
Excessive calorie restriction can slow your metabolism, increase muscle loss, and trigger survival mechanisms that make fat loss harder.
On the flip side, eating frequently, even if it’s healthy, can keep insulin elevated, blocking fat burning.
✅ Fix it with: Smart intermittent fasting, eating protein-rich meals 2–3 times/day, and letting your insulin drop between meals.
Your gut bacteria play a direct role in:
Dysbiosis (imbalanced gut bacteria) or leaky gut can make your body more inflamed and resistant to weight loss.
✅ Fix it with: A gut-healing protocol (glutamine, zinc carnosine, probiotics), reducing processed foods, and testing for hidden infections or candida.
When your body is inflamed, it prioritizes healing, not fat burning. Inflammation also increases cortisol and worsens insulin resistance.
Common causes include:
✅ Fix it with: Anti-inflammatory diet, omega-3s, turmeric, grounding, and toxin testing if needed.
Estrogen, progesterone, and testosterone all impact:
Imbalances in perimenopause, menopause, or andropause can lead to:
✅ Fix it with: Hormone testing (DUTCH test, blood work), targeted supplementation, and hormone replacement therapy when appropriate.
Sometimes, the issue isn’t obvious. You could be dealing with:
These can all quietly block fat loss even when your diet and exercise are perfect.
✅ Fix it with: Functional lab testing, targeted detox support, and optimizing mitochondria and nutrients.
Too much cardio + not enough resistance training = muscle loss + metabolic slowdown.
Overexercising can also raise cortisol and stress your system, especially if paired with low-calorie intake.
✅ Fix it with:
At Sheen Vein & Cosmetics, we don’t believe in cookie-cutter weight loss plans. We help you uncover the root causes of stubborn weight and design a plan that supports your unique biology.
Our comprehensive evaluations include:
Whether you’ve tried diets, exercise programs, or weight loss medications—we help you finally understand why your body is stuck and how to move forward.
We specialize in helping people who feel like they’ve tried everything. If you're wondering why the weight won’t come off, it’s time to dig deeper.
🌐 Visit our website to learn about our functional weight loss approach
📍 Or call us to schedule your personalized consult at Sheen Vein & Cosmetics