How PRP and PRF Can Transform Facial Aesthetics Naturally

Harnessing Your Body’s Own Healing Power for Skin Rejuvenation

In aesthetic medicine, some of the most impressive results come from working with what the body already knows how to do best—heal and regenerate. That’s exactly the principle behind Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF) facial treatments. By using a patient’s own concentrated platelets, these therapies stimulate collagen, improve texture, and naturally restore a youthful appearance—without the need for synthetic fillers or harsh chemicals.

At Sheen Vein (Aesthetics and Functional Medicine) here in St. Louis, we’ve seen PRP and PRF deliver remarkable, natural-looking results for patients who want to age gracefully while enhancing skin health from the inside out.

PRP vs. PRF – Understanding the Difference

Both PRP and PRF come from a small blood draw. The difference lies in how they’re prepared and how they release growth factors:

  • PRP (Platelet-Rich Plasma): Spun in a centrifuge at higher speeds to isolate plasma rich in platelets. This plasma contains growth factors that accelerate healing and collagen production.
  • PRF (Platelet-Rich Fibrin): Processed at lower speeds without anticoagulants, allowing for a fibrin matrix to form. This creates a slower, sustained release of growth factors over several days, leading to longer-lasting rejuvenation.

Think of PRP as a quick boost and PRF as a time-release capsule—both effective, but PRF tends to provide more prolonged stimulation for the skin.

How PRP and PRF Improve Facial Aesthetics

1. Boosting Collagen and Elastin Production

Collagen is the scaffolding of youthful skin. As we age, collagen production slows, leading to sagging, fine lines, and wrinkles. PRP and PRF both stimulate fibroblasts to produce new collagen and elastin, improving firmness and elasticity. Over time, patients notice a smoother, tighter complexion.

2. Enhancing Skin Texture and Tone

PRP and PRF are rich in growth factors that increase cellular turnover. This helps diminish rough patches, enlarged pores, and uneven pigmentation, resulting in a healthier, more even skin tone.

3. Improving Under-Eye Hollows and Dark Circles

The under-eye area is notoriously difficult to treat because the skin is thin and delicate. PRF in particular works beautifully here—it can improve volume loss, brighten dark circles, and strengthen the skin’s structure without the risk of overfilling.

4. Accelerating Healing After Other Procedures

When paired with treatments like microneedling, laser resurfacing, or RF skin tightening, PRP and PRF can dramatically shorten downtime and enhance results. We often combine therapies in our St. Louis clinic to maximize collagen stimulation and skin regeneration.

What to Expect During a PRP or PRF Facial Treatment

  1. Consultation & Skin Assessment – We evaluate your skin health, goals, and medical history to determine the right approach.
  2. Blood Draw & Processing – A small amount of blood is drawn and placed in a specialized centrifuge to isolate PRP or PRF.
  3. Application – Depending on your treatment plan, PRP/PRF is either injected into targeted areas (like cheeks, jawline, or under eyes) or applied topically after microneedling.
  4. Recovery & Results – Minimal downtime is typical. Most patients notice improvements in texture and glow within weeks, with collagen remodeling continuing for months.

How Long Do Results Last?

  • PRP: Results often last 6–12 months, with maintenance sessions recommended for best outcomes.
  • PRF: Because it releases growth factors more slowly, results can last longer—often up to 12–18 months depending on skin health and lifestyle.

Many of our patients opt for a series of treatments, spaced 4–6 weeks apart, followed by yearly touch-ups to maintain results.

Why Patients Choose PRP/PRF Over Fillers Alone

While dermal fillers remain a popular option for restoring lost volume, PRP and PRF address the quality of the skin in ways fillers cannot. By stimulating collagen and improving microcirculation, these treatments create healthier, more resilient skin from within. In fact, many patients use PRF as a complement to fillers for a balanced, natural look.

Is PRP or PRF Right for You?

These treatments are ideal for men and women who:

  • Want to improve fine lines, wrinkles, and skin laxity
  • Have thinning skin under the eyes or early hollowing
  • Prefer natural, autologous therapies
  • Are looking to enhance the results of other procedures
  • Want a healthy, youthful glow without looking “done”

Experience PRP and PRF in St. Louis

At Sheen Vein (Aesthetics and Functional Medicine), we take a personalized approach to facial rejuvenation. Using advanced platelet therapy techniques, we help patients achieve noticeable yet natural results—restoring not just beauty, but confidence.

If you’re curious about how PRP or PRF can help you look refreshed and radiant, schedule your consultation today. Your body already has the tools—it’s time to put them to work for your skin.